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Critical Role for Caspase-8 in EGF Signaling

Caspase-8 has a well defined canonical role as an apical protease of the extrinsic apoptosis pathway. Evidence is growing, however, that the protein has numerous other non-apoptotic functions. We have previously demonstrated that caspase-8 is required for efficient adhesion-induced activation of the...

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Autors principals: Finlay, Darren, Howes, Amy, Vuori, Kristiina
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711543/
https://ncbi.nlm.nih.gov/pubmed/19470771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3731
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