Molecular Mechanism of Distinct Salt-Dependent Enzyme Activity of Two Halophilic Nucleoside Diphosphate Kinases

Nucleoside diphosphate kinases from haloarchaea Haloarcula quadrata (NDK-q) and H. sinaiiensis (NDK-s) are identical except for one out of 154 residues, i.e., Arg(31) in NDK-q and Cys(31) in NDK-s. However, the salt-dependent activity profiles of NDK-q and NDK-s are quite different: the optimal NaCl...

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Detalhes bibliográficos
Main Authors: Yamamura, Akihiro, Ichimura, Takefumi, Kamekura, Masahiro, Mizuki, Toru, Usami, Ron, Makino, Tsukasa, Ohtsuka, Jun, Miyazono, Ken-ichi, Okai, Masahiko, Nagata, Koji, Tanokura, Masaru
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Protein
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711501/
https://ncbi.nlm.nih.gov/pubmed/19486691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.012
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