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Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer

PURPOSE: Aberrant activation of the Notch signaling pathway is commonly observed in human pancreatic cancer, although the mechanisms for this activation have not been elucidated. EXPERIMENTAL DESIGN: A panel of 20 human pancreatic cancer cell lines was profiled for the expression of Notch pathway re...

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Autors principals: Mullendore, Michael E., Koorstra, Jan-Bart, Li, Yue-Ming, Offerhaus, G. Johan, Fan, Xing, Henderson, Clark M., Bisht, Savita, Matsui, William, Eberhart, Charles G., Maitra, Anirban, Feldmann, Georg
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711441/
https://ncbi.nlm.nih.gov/pubmed/19258443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2004
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