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Precision Surface-Coupled Optical-Trapping Assay with One-Basepair Resolution
The most commonly used optical-trapping assays are coupled to surfaces, yet such assays lack atomic-scale (∼0.1 nm) spatial resolution due to drift between the surface and trap. We used active stabilization techniques to minimize surface motion to 0.1 nm in three dimensions and decrease multiple typ...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711297/ https://ncbi.nlm.nih.gov/pubmed/19348774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3933 |
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