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Mechanism and Energetics of Charybdotoxin Unbinding from a Potassium Channel from Molecular Dynamics Simulations

Ion channel-toxin complexes are ideal systems for computational studies of protein-ligand interactions, because, in most cases, the channel axis provides a natural reaction coordinate for unbinding of a ligand and a wealth of physiological data is available to check the computational results. We use...

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Bibliografische gegevens
Hoofdauteurs: Chen, Po-chia, Kuyucak, Serdar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711292/
https://ncbi.nlm.nih.gov/pubmed/19348743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3952
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