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A Kinetic Model of Trp-Cage Folding from Multiple Biased Molecular Dynamics Simulations

Trp-cage is a designed 20-residue polypeptide that, in spite of its size, shares several features with larger globular proteins. Although the system has been intensively investigated experimentally and theoretically, its folding mechanism is not yet fully understood. Indeed, some experiments suggest...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Marinelli, Fabrizio, Pietrucci, Fabio, Laio, Alessandro, Piana, Stefano
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711228/
https://ncbi.nlm.nih.gov/pubmed/19662155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000452
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