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Watching the watcher: regulation of p53 by mitochondria

p53 has been referred to as the ‘guardian of the genome’ because of its role in protecting the cell from DNA damage. p53 performs its duties by regulating cell-cycle progression and DNA repair and, in cases of irreparable DNA damage, by executing programmed cell death. Mitochondria are an important...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Holley, Aaron K, St Clair, Daret K
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710969/
https://ncbi.nlm.nih.gov/pubmed/19243304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14796694.5.1.117
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