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Watching the watcher: regulation of p53 by mitochondria
p53 has been referred to as the ‘guardian of the genome’ because of its role in protecting the cell from DNA damage. p53 performs its duties by regulating cell-cycle progression and DNA repair and, in cases of irreparable DNA damage, by executing programmed cell death. Mitochondria are an important...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710969/ https://ncbi.nlm.nih.gov/pubmed/19243304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14796694.5.1.117 |
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