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IL-15 produced and trans-presented by DCs underlies homeostatic competition between CD8 and γδ T cells in vivo
Homeostatic mechanism by which peripheral T-cell subsets are maintained in vivo remains largely unknown. Using a T-cell proliferation model under lymphopenic settings, we now demonstrate that γδ T cells limit CD8 T-cell expansion but not the initial proliferation after transfer into lymphopenic reci...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710929/ https://ncbi.nlm.nih.gov/pubmed/19380870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-192997 |
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