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A CELL-BASED MOLECULAR TRANSPORT SIMULATOR FOR PHARMACOKINETIC PREDICTION AND CHEMINFORMATIC EXPLORATION

In the body, cell monolayers serve as permeability barriers, determining transport of drug molecules from one organ or tissue compartment to another. After oral administration, for example, drug transport across the epithelial cell monolayer lining the lumen of the intestine determines the fraction...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Xinyuan, Shedden, Kerby, Rosania, Gus R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710883/
https://ncbi.nlm.nih.gov/pubmed/17140258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp060046k
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