Backup in gene regulatory networks explains differences between binding and knockout results

The complementarity of gene expression and protein–DNA interaction data led to several successful models of biological systems. However, recent studies in multiple species raise doubts about the relationship between these two datasets. These studies show that the overwhelming majority of genes bound...

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Autores principales: Gitter, Anthony, Siegfried, Zehava, Klutstein, Michael, Fornes, Oriol, Oliva, Baldo, Simon, Itamar, Bar-Joseph, Ziv
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2009
Materias:
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710864/
https://ncbi.nlm.nih.gov/pubmed/19536199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.33
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