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Bacteria capture iron from heme by keeping tetrapyrrol skeleton intact

Because heme is a major iron-containing molecule in vertebrates, the ability to use heme-bound iron is a determining factor in successful infection by bacterial pathogens. Until today, all known enzymes performing iron extraction from heme did so through the rupture of the tetrapyrrol skeleton. Here...

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Detalhes bibliográficos
Main Authors: Létoffé, Sylvie, Heuck, Gesine, Delepelaire, Philippe, Lange, Norbert, Wandersman, Cécile
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710666/
https://ncbi.nlm.nih.gov/pubmed/19564607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903842106
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