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Prenatal Immune Challenge Is an Environmental Risk Factor for Brain and Behavior Change Relevant to Schizophrenia: Evidence from MRI in a Mouse Model

OBJECTIVES: Maternal infection during pregnancy increases risk of severe neuropsychiatric disorders, including schizophrenia and autism, in the offspring. The most consistent brain structural abnormality in patients with schizophrenia is enlarged lateral ventricles. However, it is unknown whether th...

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Main Authors: Li, Qi, Cheung, Charlton, Wei, Ran, Hui, Edward S., Feldon, Joram, Meyer, Urs, Chung, Sookja, Chua, Siew E., Sham, Pak C., Wu, Ed X., McAlonan, Grainne M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710518/
https://ncbi.nlm.nih.gov/pubmed/19629183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006354
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