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A Single, Mild, Transient Scrotal Heat Stress Causes Hypoxia and Oxidative Stress in Mouse Testes, Which Induces Germ Cell Death

Spermatogenesis is a temperature-dependent process, and increases in scrotal temperature can disrupt its progression. We previously showed that heat stress causes DNA damage in germ cells, an increase in germ cell death (as seen on TUNEL staining), and subfertility. The present study evaluated the s...

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Autors principals: Paul, Catriona, Teng, Serena, Saunders, Philippa T.K.
Format: Artigo
Idioma:Inglês
Publicat: Society for the Study of Reproduction, Inc. 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709966/
https://ncbi.nlm.nih.gov/pubmed/19144962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.071779
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