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The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons

Some of the tryptophan catabolites produced through the kynurenine pathway (KP), and more particularly the excitotoxin quinolinic acid (QA), are likely to play a role in the pathogenesis of Alzheimer's disease (AD). We have previously shown that the KP is over activated in AD brain and that QA...

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Autors principals: Rahman, Abdur, Ting, Kaka, Cullen, Karen M., Braidy, Nady, Brew, Bruce J., Guillemin, Gilles J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709912/
https://ncbi.nlm.nih.gov/pubmed/19623258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006344
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