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Oxidative DNA damage precedes DNA fragmentation after experimental stroke in rat brain

Experimental stroke using a focal cerebral ischemia and reperfusion (FCIR) model was induced in male Long-Evans rats by a bilateral occlusion of both common carotid arteries and the right middle cerebral artery for 30–90 min, followed by various periods of reperfusion. Oxidative DNA lesions in the i...

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Autori principali: CUI, JIANKUN, HOLMES, ERIC H., GREENE, THOMAS G., LIU, PHILIP K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709847/
https://ncbi.nlm.nih.gov/pubmed/10783150
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