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Perineural Administration of Dexmedetomidine in Combination with Bupivacaine Enhances Sensory and Motor Blockade in Sciatic Nerve Block without Inducing Neurotoxicity in the Rat

BACKGROUND: The present study was designed to test the hypothesis that high-dose dexmedetomidine added to local anesthetic would increase the duration of sensory and motor blockade in a rat model of sciatic nerve blockade without causing nerve damage. METHODS: Thirty-one adult Sprague Dawley rats re...

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Библиографические подробности
Главные авторы: Brummett, Chad M., Norat, Mary A., Palmisano, John M., Lydic, Ralph
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709835/
https://ncbi.nlm.nih.gov/pubmed/18719449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318182c26b
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