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Origin of the Stability Conferred upon Collagen by Fluorination
According to a prevailing theory, (2S,4R)-4-hydroxyproline (Hyp) residues stabilize the collagen triple helix via a stereoelectronic effect that preorganizes appropriate backbone torsion angles for triple-helix formation. This theory is consistent with the marked stability that results from replacin...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709698/ https://ncbi.nlm.nih.gov/pubmed/19423349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.03.168 |
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