The E-Selectin Ligand Basigin/CD147 Is Responsible for Neutrophil Recruitment in Renal Ischemia/Reperfusion

E-selectin and its ligands are essential for extravasation of leukocytes in inflammation. Here, we report that basigin (Bsg)/CD147 is a ligand for E-selectin that promotes renal inflammation in ischemia/reperfusion. Compared with wild-type mice, Bsg-deficient (Bsg(−/−)) mice demonstrated striking su...

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Hlavní autoři: Kato, Noritoshi, Yuzawa, Yukio, Kosugi, Tomoki, Hobo, Akinori, Sato, Waichi, Miwa, Yuko, Sakamoto, Kazuma, Matsuo, Seiichi, Kadomatsu, Kenji
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2009
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709679/
https://ncbi.nlm.nih.gov/pubmed/19443639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008090957
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