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Cytokine-dependent and–independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling

BACKGROUND: The requirements for growth and survival of the intracellular pathogen Trypanosoma cruzi within mammalian host cells are poorly understood. Transcriptional profiling of the host cell response to infection serves as a rapid read-out for perturbation of host physiology that, in part, refle...

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Bibliographic Details
Main Authors: Costales, Jaime A, Daily, Johanna P, Burleigh, Barbara A
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709661/
https://ncbi.nlm.nih.gov/pubmed/19480704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-252
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