Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease

BACKGROUND: New strategies for the treatment of Parkinson's disease (PD) are shifted from dopamine (DA) replacement to regeneration or restoration of the nigro-striatal system. A cell therapy using human retinal pigment epithelial (RPE) cells as substitution for degenerated dopaminergic (DAergi...

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Detalhes bibliográficos
Main Authors: Ming, Ming, Li, Xuping, Fan, Xiaolan, Yang, Dehua, Li, Liang, Chen, Sheng, Gu, Qing, Le, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709608/
https://ncbi.nlm.nih.gov/pubmed/19558709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-7-53
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