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Methyl Group Migration during the Fragmentation of Singly Charged Ions of Trimethyllysine-containing Peptides: Precaution of Using MS/MS of Singly Charged Ions for Interrogating Peptide Methylation

Core histones are susceptible to a range of post-translational modifications (PTMs), including acetylation, phosphorylation, methylation and ubiquitination, which play important roles in the epigenetic control of gene expression. Here, we observed an unusual discrepancy between MALDI-MS/MS and ESI-M...

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Bibliografiske detaljer
Main Authors: Xiong, Lei, Ping, Liyan, Yuan, Bifeng, Wang, Yinsheng
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709603/
https://ncbi.nlm.nih.gov/pubmed/19303795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2009.02.014
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