CD73-generated Adenosine Restricts Lymphocyte Migration into Draining Lymph Nodes

After an inflammatory stimulus, lymphocyte migration into draining lymph nodes increases dramatically to facilitate the encounter of naïve T cells with antigen-loaded dendritic cells. Here we show that CD73 (ecto-5′-nucleotidase) plays an important role in regulating this process. CD73 produces aden...

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Hauptverfasser: Takedachi, Masahide, Qu, Dongfeng, Ebisuno, Yukihiko, Oohara, Hiroyuki, Joachims, Michelle L., McGee, Stephanie T., Maeda, Emiko, McEver, Rodger P., Tanaka, Toshiyuki, Miyasaka, Masayuki, Murakami, Shinya, Krahn, Thomas, Blackburn, Michael R., Thompson, Linda F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709497/
https://ncbi.nlm.nih.gov/pubmed/18424752
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