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Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon

11q13 amplification is a late-stage event in several cancers that is often associated with poor prognosis. Among 11q13-amplified genes, the actin assembly protein cortactin/CTTN is considered a likely candidate for direct involvement in tumor progression, because of its cell motility-enhancing funct...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Clark, Emily S., Brown, Brandee, Whigham, Amy S., Kochaishvili, Avtandyl, Yarbrough, Wendell G., Weaver, Alissa M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709457/
https://ncbi.nlm.nih.gov/pubmed/18931703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.389
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