The Role of Akt/Protein Kinase B Subtypes in Retinal Ischemic Preconditioning

PURPOSE: Potent endogenous protection from ischemia can be induced in the retina by ischemic preconditioning (IPC). Protein kinase B/Akt is a cellular survival factor. We hypothesized that Akt was integral to IPC based upon differential effects of Akt subtypes. METHODS: Rats were subjected to retina...

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Main Authors: Dreixler, John C., Hemmert, Jonathan W., Shenoy, Shanti K., Shen, Yang, Lee, H. Thomas, Shaikh, Afzhal R., Rosenbaum, Daniel M., Roth, Steven
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709455/
https://ncbi.nlm.nih.gov/pubmed/19084003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2008.11.013
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