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Loss of α-Catenin Decreases the Strength of Single E-cadherin Bonds between Human Cancer Cells

The progression of several human cancers correlates with the loss of cytoplasmic protein α-catenin from E-cadherin-rich intercellular junctions and loss of adhesion. However, the potential role of α-catenin in directly modulating the adhesive function of individual E-cadherin molecules in human canc...

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Main Authors: Bajpai, Saumendra, Feng, Yunfeng, Krishnamurthy, Ranjini, Longmore, Gregory D., Wirtz, Denis
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709389/
https://ncbi.nlm.nih.gov/pubmed/19458087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.000661
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