Up-regulation of miR-21 by HER2/neu Signaling Promotes Cell Invasion

The cell surface receptor tyrosine kinase HER2/neu enhances tumor metastasis. Recent studies suggest that deregulated microRNA (miRNA) expression promotes invasion and metastasis of cancer cells; we therefore explored the possibility that HER2/neu signaling induces the expression of specific miRNAs...

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Dettagli Bibliografici
Autori principali: Huang, Tzu-Hsuan, Wu, Fangting, Loeb, Gabriel B., Hsu, Ruby, Heidersbach, Amy, Brincat, Allison, Horiuchi, Dai, Lebbink, Robert J., Mo, Yin-Yuan, Goga, Andrei, McManus, Michael T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
RNA-Mediated Regulation and Noncoding RNAs
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709372/
https://ncbi.nlm.nih.gov/pubmed/19419954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006676
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