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Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

BACKGROUND: Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) lack stable tertiary and/or secondary structure yet fulfills key biological functions. The recent recognition of IDPs and IDRs is leading to an entire field aimed at their systematic structural character...

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Detalhes bibliográficos
Main Authors: Uversky, Vladimir N, Oldfield, Christopher J, Midic, Uros, Xie, Hongbo, Xue, Bin, Vucetic, Slobodan, Iakoucheva, Lilia M, Obradovic, Zoran, Dunker, A Keith
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709268/
https://ncbi.nlm.nih.gov/pubmed/19594884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-S1-S7
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