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Reverse engineering module networks by PSO-RNN hybrid modeling

BACKGROUND: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reasons: (1) thousands of genes are involved in one living cell; (2) complex dynamic and nonlinear relationships exist among...

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Detalhes bibliográficos
Main Authors: Zhang, Yuji, Xuan, Jianhua, de los Reyes, Benildo G, Clarke, Robert, Ressom, Habtom W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709258/
https://ncbi.nlm.nih.gov/pubmed/19594874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-S1-S15
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