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An In-solution Ultrasonication-assisted Digestion Method for Improved Extracellular Matrix Proteome Coverage

Epithelial cell behavior is coordinated by the composition of the surrounding extracellular matrix (ECM); thus ECM protein identification is critical for understanding normal biology and disease states. Proteomic analyses of ECM proteins have been hindered by the insoluble and digestion-resistant na...

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Bibliographic Details
Main Authors: Hansen, Kirk C., Kiemele, Lauren, Maller, Ori, O'Brien, Jenean, Shankar, Aarthi, Fornetti, Jaime, Schedin, Pepper
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709248/
https://ncbi.nlm.nih.gov/pubmed/19351662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900039-MCP200
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