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Synthesis of an experimental glycolipoprotein vaccine against Lyme disease

A novel glycolipid was synthesized that corresponds to cholesteryl palmitoyl-galactopyranoside 1 found in the spirochete Borrelia burgdorferi, the causative agent of Lyme disease. In order to fashion 1 in a conjugatable form, the palmitoyl residue was modified to include a terminal aldehydo moiety t...

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Hlavní autoři: Pozsgay, Vince, Kubler-Kielb, Joanna
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709212/
https://ncbi.nlm.nih.gov/pubmed/17182019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2006.11.014
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