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Atypical X-Chromosome Inactivation in an X;1 Translocation Patient Demonstrating Xq28 Functional Disomy

X-chromosome inactivation is an epigenetic process used to regulate gene dosage in mammalian females by silencing genes on one X-chromosome. While the pattern of X-chromosome inactivation is typically random in normal females, abnormalities of the X-chromosome may result in skewing due to disadvanta...

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Detalhes bibliográficos
Main Authors: Cottrell, Catherine E, Sommer, Annemarie, Wenger, Gail D, Bullard, Steven, Busch, Tamara, Krahn, Katherine Nash, Lidral, Andrew C, Gastier-Foster, Julie M
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709101/
https://ncbi.nlm.nih.gov/pubmed/19215059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.32699
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