The ENTH domain protein Clint1 is required for epidermal homeostasis in zebrafish

Epidermal hyperproliferation and inflammation are hallmarks of the human condition psoriasis. Here, we report that a zebrafish line with a mutation in the cargo adaptor protein Clint1 exhibits psoriasis-like phenotypes including epithelial hyperproliferation and leukocyte infiltration. Clint1 is an...

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Autors principals: Dodd, M. Ernest, Hatzold, Julia, Mathias, Jonathan R., Walters, Kevin B., Bennin, David A., Rhodes, Jennifer, Kanki, John P., Look, A. Thomas, Hammerschmidt, Matthias, Huttenlocher, Anna
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709065/
https://ncbi.nlm.nih.gov/pubmed/19570844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.038448
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