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Systematic identification of mammalian regulatory motifs' target genes and functions
We have developed an algorithm (“Lever”) that systematically maps metazoan DNA regulatory motifs or motif combinations to the sets of genes that they likely regulate. Lever accomplishes this by assessing whether the motifs are enriched within cis regulatory modules (CRMs), predicted by our “PhylCRM”...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708972/ https://ncbi.nlm.nih.gov/pubmed/18311145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1188 |
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