Bcl-2 Expression and p38MAPK Activity in Cells Infected with Influenza A Virus: IMPACT ON VIRALLY INDUCED APOPTOSIS AND VIRAL REPLICATION

Previous reports have shown that various steps in the influenza A virus life cycle are impaired in cells expressing the antiapoptotic protein Bcl-2 (Bcl-2(+) cells). We demonstrated a direct link between Bcl-2 and the reduced nuclear export of viral ribonucleoprotein (vRNP) complexes in these cells....

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Detalhes bibliográficos
Main Authors: Nencioni, Lucia, De Chiara, Giovanna, Sgarbanti, Rossella, Amatore, Donatella, Aquilano, Katia, Marcocci, Maria E., Serafino, Annalucia, Torcia, Maria, Cozzolino, Federico, Ciriolo, Maria R., Garaci, Enrico, Palamara, Anna T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708894/
https://ncbi.nlm.nih.gov/pubmed/19336399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900146200
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