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Catalytic Domain Architecture of Metzincin Metalloproteases

Metalloproteases cleave proteins and peptides, and deregulation of their function leads to pathology. An understanding of their structure and mechanisms of action is necessary to the development of strategies for their regulation. Among metallopeptidases are the metzincins, which are mostly multidom...

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Autore principale: Gomis-Rüth, F. Xavier
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708831/
https://ncbi.nlm.nih.gov/pubmed/19201757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800069200
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