Luminal Cathepsin G and Protease-Activated Receptor 4 : A Duet Involved in Alterations of the Colonic Epithelial Barrier in Ulcerative Colitis

Impairment of the colonic epithelial barrier and neutrophil infiltration are common features of inflammatory bowel disease. Luminal proteases affect colonic permeability through protease-activated receptors (PARs). We evaluated: (i) whether fecal supernatants from patients with ulcerative colitis (U...

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Bibliografski detalji
Glavni autori: Dabek, Marta, Ferrier, Laurent, Roka, Richard, Gecse, Krisztina, Annahazi, Anita, Moreau, Jacques, Escourrou, Jean, Cartier, Christel, Chaumaz, Gilles, Leveque, Mathilde, Ait-Belgnaoui, Afifa, Wittmann, Tibor, Theodorou, Vassilia, Bueno, Lionel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2009
Teme:
Regular Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708807/
https://ncbi.nlm.nih.gov/pubmed/19528350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080986
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