Luminal Cathepsin G and Protease-Activated Receptor 4 : A Duet Involved in Alterations of the Colonic Epithelial Barrier in Ulcerative Colitis

Impairment of the colonic epithelial barrier and neutrophil infiltration are common features of inflammatory bowel disease. Luminal proteases affect colonic permeability through protease-activated receptors (PARs). We evaluated: (i) whether fecal supernatants from patients with ulcerative colitis (U...

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Detalhes bibliográficos
Main Authors: Dabek, Marta, Ferrier, Laurent, Roka, Richard, Gecse, Krisztina, Annahazi, Anita, Moreau, Jacques, Escourrou, Jean, Cartier, Christel, Chaumaz, Gilles, Leveque, Mathilde, Ait-Belgnaoui, Afifa, Wittmann, Tibor, Theodorou, Vassilia, Bueno, Lionel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708807/
https://ncbi.nlm.nih.gov/pubmed/19528350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080986
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