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Luminal Cathepsin G and Protease-Activated Receptor 4 : A Duet Involved in Alterations of the Colonic Epithelial Barrier in Ulcerative Colitis

Impairment of the colonic epithelial barrier and neutrophil infiltration are common features of inflammatory bowel disease. Luminal proteases affect colonic permeability through protease-activated receptors (PARs). We evaluated: (i) whether fecal supernatants from patients with ulcerative colitis (U...

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Main Authors: Dabek, Marta, Ferrier, Laurent, Roka, Richard, Gecse, Krisztina, Annahazi, Anita, Moreau, Jacques, Escourrou, Jean, Cartier, Christel, Chaumaz, Gilles, Leveque, Mathilde, Ait-Belgnaoui, Afifa, Wittmann, Tibor, Theodorou, Vassilia, Bueno, Lionel
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708807/
https://ncbi.nlm.nih.gov/pubmed/19528350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080986
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