Luminal Cathepsin G and Protease-Activated Receptor 4 : A Duet Involved in Alterations of the Colonic Epithelial Barrier in Ulcerative Colitis

Impairment of the colonic epithelial barrier and neutrophil infiltration are common features of inflammatory bowel disease. Luminal proteases affect colonic permeability through protease-activated receptors (PARs). We evaluated: (i) whether fecal supernatants from patients with ulcerative colitis (U...

Full description

Saved in:
Bibliographic Details
Main Authors: Dabek, Marta, Ferrier, Laurent, Roka, Richard, Gecse, Krisztina, Annahazi, Anita, Moreau, Jacques, Escourrou, Jean, Cartier, Christel, Chaumaz, Gilles, Leveque, Mathilde, Ait-Belgnaoui, Afifa, Wittmann, Tibor, Theodorou, Vassilia, Bueno, Lionel
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2009
Subjects:
Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708807/
https://ncbi.nlm.nih.gov/pubmed/19528350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080986
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items