The Influence of Tumor-Host Interactions in the Stromal Cell-Derived Factor-1/CXCR4 Ligand/Receptor Axis in Determining Metastatic Risk in Breast Cancer

The chemokine stromal cell-derived factor-1 (SDF-1) may function to attract CXCR4-expressing cancer cells to metastatic organs. We have previously demonstrated that low plasma SDF-1, a host-derived marker, increases distant metastatic risk in breast cancer. We therefore hypothesized that tumors over...

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Detalhes bibliográficos
Main Authors: Hassan, Saima, Ferrario, Cristiano, Saragovi, Uri, Quenneville, Louise, Gaboury, Louis, Baccarelli, Andrea, Salvucci, Ombretta, Basik, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708795/
https://ncbi.nlm.nih.gov/pubmed/19497995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080948
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