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A Y526Q Mutation in the Newcastle Disease Virus HN Protein Reduces Its Functional Activities and Attenuates Virus Replication and Pathogenicity

The hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) is a multifunctional protein that plays a crucial role in virus infectivity. In this study, using the mesogenic strain Beaudette C (BC), we mutated three conserved amino acids thought to be part of the binding/catalytic ac...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Khattar, Sunil K., Yan, Yongqi, Panda, Aruna, Collins, Peter L., Samal, Siba K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708642/
https://ncbi.nlm.nih.gov/pubmed/19474107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00536-09
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