Benzene-Induced Hematopoietic Neoplasms Including Myeloid Leukemia in Trp53-Deficient C57BL/6 and C3H/He Mice

This research focused on three major questions regarding benzene-induced hematopoietic neoplasms (HPNs). First, why are HPNs induced equivocally and at only threshold level with low-dose benzene exposure despite the significant genotoxicity of benzene even at low doses both in experiments and in epi...

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Hlavní autoři: Kawasaki, Yasushi, Hirabayashi, Yoko, Kaneko, Toyozo, Kanno, Jun, Kodama, Yukio, Matsushima, Yuuko, Ogawa, Yukio, Saitoh, Minoru, Sekita, Kiyoshi, Uchida, Osayuki, Umemura, Takashi, Yoon, Byung-Il, Inoue, Tohru
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Carcinogenicity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708599/
https://ncbi.nlm.nih.gov/pubmed/19478238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp107
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