Purification of Legiobactin and Importance of This Siderophore in Lung Infection by Legionella pneumophila

When cultured in a low-iron medium, Legionella pneumophila secretes a siderophore (legiobactin) that is both reactive in the chrome azurol S (CAS) assay and capable of stimulating the growth of iron-starved legionellae. Using anion-exchange high-pressure liquid chromatography (HPLC), we purified leg...

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Main Authors: Allard, Kimberly A., Dao, Jenny, Sanjeevaiah, Prakash, McCoy-Simandle, Kessler, Chatfield, Christa H., Crumrine, David S., Castignetti, Domenic, Cianciotto, Nicholas P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Bacterial Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708552/
https://ncbi.nlm.nih.gov/pubmed/19398549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00087-09
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