Anti-Apical-Membrane-Antigen-1 Antibody Is More Effective than Anti-42-Kilodalton-Merozoite-Surface-Protein-1 Antibody in Inhibiting Plasmodium falciparum Growth, as Determined by the In Vitro Growth Inhibition Assay

Apical membrane antigen 1 (AMA1) and the 42-kDa merozoite surface protein 1 (MSP1(42)) are leading malaria vaccine candidates. Several preclinical and clinical trials have been conducted, and an in vitro parasite growth inhibition assay has been used to evaluate the biological activities of the resu...

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Main Authors: Miura, Kazutoyo, Zhou, Hong, Diouf, Ababacar, Moretz, Samuel E., Fay, Michael P., Miller, Louis H., Martin, Laura B., Pierce, Mark A., Ellis, Ruth D., Mullen, Gregory E. D., Long, Carole A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Vaccine Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708396/
https://ncbi.nlm.nih.gov/pubmed/19439523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00042-09
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