Chronic administration of morphine is associated with a decrease in surface AMPA GluR1 receptor subunit in dopamine D1 receptor expressing neurons in the shell and non-D1 receptor expressing neurons in the core of the rat nucleus accumbens

The nucleus accumbens (Acb) is an extensively studied neuroanatomical substrate of opiate reward and the neural plasticity associated with chronic opioid use. The cellular mechanisms mediating opioid-dependent plasticity are uncertain, however AMPA-type glutamate receptor trafficking in dopamine D1...

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Main Authors: Glass, Michael J., Lane, Diane A., Colago, Eric E.O., Chan, June, Schlussman, Stefan D., Zhou, Yan, Kreek, Mary Jeanne, Virginia, M. Pickel
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708174/
https://ncbi.nlm.nih.gov/pubmed/18294632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.01.012
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