Molecular Mechanisms and Physiological Significance of Autophagy during Myocardial Ischemia and Reperfusion

Autophagy is an intracellular bulk degradation process whereby cytoplasmic proteins and organelles are degraded and recycled through lysosomes. In the heart, autophagy plays a homeostatic role at basal levels, and the absence of autophagy causes cardiac dysfunction and the development of cardiomyopa...

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Main Authors: Matsui, Yutaka, Kyoi, Shiori, Takagi, Hiromitsu, Hsu, Chiao-Po, Hariharan, Nirmala, Ago, Tetsuro, Vatner, Stephen F, Sadoshima, Junichi
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708091/
https://ncbi.nlm.nih.gov/pubmed/18227645
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