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Assessing Outcomes in Prostate Cancer Clinical Trials: A 21st Century Tower of Babel

BACKGROUND: Due to the osseous distribution of prostate cancer metastases, progression is more readily identified than response in prostate cancer clinical trials. As a result, there is an increased focus on progression free survival (PFS) as a phase II endpoint. PFS, however, is vulnerable to inter...

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Autors principals: Gignac, Gretchen A., Morris, Michael J., Heller, Glenn, Schwartz, Lawrence H., Scher, Howard I.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708077/
https://ncbi.nlm.nih.gov/pubmed/18661513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.23719
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