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Walker-A threonine couples nucleotide occupancy with the chaperone activity of the AAA+ ATPase ClpB
Hexameric AAA+ ATPases induce conformational changes in a variety of macromolecules. AAA+ structures contain the nucleotide-binding P-loop with the Walker A sequence motif: GxxGxGK(T/S). A subfamily of AAA+ sequences contains Asn in the Walker A motif instead of Thr or Ser. This noncanonical subfami...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708065/ https://ncbi.nlm.nih.gov/pubmed/19177562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.36 |
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