Ciprofloxacin decreases survival in HT-29 cells via the induction of TGF-β1 secretion and enhances the anti-proliferative effect of 5-fluorouracil

BACKGROUND AND PURPOSE: Fluoroquinolones are potent anti-microbial agents with multiple effects on host cells and tissues. Previous studies have highlighted their pro-apoptotic effect on human cancer cells and an immunoregulatory role in animal models of inflammatory bowel disease. We examined the e...

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Detalhes bibliográficos
Main Authors: Bourikas, Leonidas A, Kolios, George, Valatas, Vassilis, Notas, George, Drygiannakis, Ioannis, Pelagiadis, Iordanis, Manousou, Pinelopi, Klironomos, Stefanos, Mouzas, Ioannis A, Kouroumalis, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707983/
https://ncbi.nlm.nih.gov/pubmed/19371339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00161.x
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