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Mechanisms of U46619-induced contraction of rat pulmonary arteries in the presence and absence of the endothelium

BACKGROUND AND PURPOSE: Thromboxane A(2) and endothelial dysfunction are implicated in the development of pulmonary hypertension. The receptor-transduction pathway for U46619 (9,11-dideoxy-9α, 11α-methanoepoxy prostaglandin F(2α))-induced contraction was examined in endothelium-intact (E+) and denud...

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Autors principals: McKenzie, C, MacDonald, A, Shaw, AM
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707971/
https://ncbi.nlm.nih.gov/pubmed/19389160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00084.x
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